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The Toenail Fungus Trial

For adults aged 18–70 living with mild-to-moderate toenail fungal infection. Conducted at our South Bank clinic in Brisbane and Sippy Downs on the Sunshine Coast.
Age 18-80
day visits
Up to $1650
About this trial

A potential new treatment to protect your kidneys from diabetes-related damage

Toenail fungus, also known as onychomycosis, is a common condition caused by a fungal infection of the toenail. It typically causes discolouration, thickening, and crumbling of the nail, and can affect daily comfort, footwear choices, and overall quality of life. Mild-to-moderate cases are widespread, yet effective treatments that are easy to use and well tolerated remain limited.

This trial is evaluating a new investigational topical solution that may offer a convenient and effective treatment option for people living with mild to moderate toenail fungal infection, applied simply at home once or twice daily, without the need for frequent clinic visits.

Examples of onychomycosis:
Toenail fungus trial
Unlike many clinical trials, this treatment is a topical solution you apply yourself at home once or twice daily, making it one of the most convenient trial commitments available, with only 7 clinic visits over 48 weeks.
Eligibility

Do you qualify?

Aged 18–80
Mild to moderate toenail fungus affecting at least 20–80% of one great (big) toenail
In generally good health
Pregnant or planning pregnancy during the trial
Used antifungal treatments in the four weeks prior to joining
What's involved

Commitment and procedures

Visit type
day visits
total visits
7+ 8 phone calls
duration
48 weeks
treatment
Topical solution

procedures

Physical examination
Vital signs monitoring
Questionnaires
Application topical solution (home)

treatment design

Eligible participants will apply the investigational topical solution to the affected toenail once or twice daily at home for 48 weeks. Participants will attend 7 clinic visits and complete 8 phone calls over the course of the study. The treatment will be evaluated against a placebo, and all procedures will be explained clearly. Participants can ask questions at any time.
More information

Have questions? We're here to help.

Contact our recruitment team directly, they're happy to answer any questions before you apply. Please do not send personal medical information by email.
Phone
+07 5409 8640
Hours
Mon–Fri, 8am–5pm
Trial at a glance
Status
enrolling
Phase
phase II
Therapeutic Area
Ages
18-80
Duration
48 weeks
Visits
7 visits, 8 phone calls
Location
Sippy Downs and Brisbane clinics
PROTOCOL
ONX-001
Reimbursement
Up to $1650

Ready to check your eligibility?

It takes less than 2 minutes to fill out our toenail fungus trial form.
Apply for this trial →
We won't share your details with third parties.
This trial has been reviewed by an independent human research ethics committee.

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UniSC Clinical Trials South East Queensland
South East Queensland's most active clinical research network, connecting communities, clinicians and global sponsors since 2015.
Study Team: 07 5409 8640
Level 1, 9 Ochre Way,
Sippy Downs, QLD 4556
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