phase I
enrolling now

The Obesity and Overweight Trial

For adults aged 18–55 who are overweight or moderately obese with a BMI between 27.5 and 39.9. Obesity and overweight trial conducted at our Morayfield clinic in Moreton Bay.
Age 18-55
day visits
Up to $8600
About this trial

Helping researchers understand how new weight medicines work in the body

Carrying extra weight is common in Australia. According to the Australian Bureau of Statistics, 65.8% of Australian adults are overweight or living with obesity. Many factors influence body weight, including diet, physical activity, environment, and genetics. While some people may not notice obvious symptoms, excess weight can sometimes be associated with lower energy levels, shortness of breath during physical activity, joint discomfort, or sleep difficulties.

Researchers continue to study how new medicines interact with the body in people living with overweight and obesity. This obesity and overweight trial focuses on understanding how an investigational weight loss medication in Australia, administered as a weekly injection, moves through the body and how people respond to different doses over time. 

By participating, you are directly contributing to broader weight management clinical research in QLD that may inform future treatment approaches.
There is a 75% chance of receiving the investigational treatment rather than a placebo. The dose is gradually increased with each cohort so researchers can observe how the body responds over time, making this a carefully monitored and progressive study.
Eligibility

Do you qualify for an obesity and overweight trial?

Aged 18–55
BMI between 27.5 and 39.9 (not sure of your BMI? Check here)
Willing to pause weight loss programs during the trial
Currently taking weight loss medicines, prescription medication or supplements for weight management
What's involved

Commitment and procedures

Visit type
day visits
total visits
27 + 4 phone calls
duration
12 weeks
treatment
Injection (once weekly)

procedures

Physical examination
Vital signs monitoring
Blood and urine sample collection
Drug and alcohol screening
Glucose tolerance test
ECG (electrocardiogram)
DEXA scan (body composition assessment)
Weekly injection of investigational treatment or placebo
Food, drink and exercise eDiary (completed daily at home)
Fat tissue sample taken under local anaesthetic (biopsy)

treatment design

Eligible participants will be randomly assigned to receive either the investigational weekly injection or a placebo, with a 75% chance of receiving the active treatment in this obesity and overweight trial. 

The injection is administered under the skin once a week during the 12-week treatment period, with the dose escalated with each cohort so researchers can observe how the body responds over time. Participants looking for medical trials for weight loss near me will attend 27 clinic visits and 4 telehealth check-ins at our Morayfield clinic, with a follow-up visit at around Day 113. 

All procedures, including the adipose tissue biopsy, will be explained clearly before you consent to take part, and participants can ask questions at any time.
More information

Have questions? We're here to help.

Contact our recruitment team directly. They're happy to answer any questions before you apply to this obesity and overweight trial. Please do not send personal medical information by email.
Phone
+07 5409 8640
Hours
Mon–Fri, 8am–5pm
Trial at a glance
Status
enrolling
Phase
phase I
Therapeutic Area
Ages
18-55
Duration
12 weeks
Visits
27 visits + 4 phone calls
Location
Morayfield clinic
PROTOCOL
RES-010-002
Reimbursement
Up to $8600

Ready to check your eligibility?

Takes less than 2 minutes to complete the obesity and overweight trial form.
Apply for this trial →
We won't share your details with third parties.
This trial has been reviewed by an independent human research ethics committee.

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