The Needle-Free Medicine Study

About this trial

Right now, nearly 180,000 Australians are living with a disease most people have never heard of, and it's growing faster here than almost anywhere else in the world. Inflammatory bowel disease (IBD) is climbing at a rate that already outpaces Canada, the UK and New Zealand, while psoriasis affects an estimated 3.68% of adults in the Australasia region, among the highest rates in the world according to the Global Psoriasis Atlas. Both conditions can bring daily pain, fatigue and disruption that isn't always visible to the people around them.

Many people with these conditions rely on injectable antibody medicines, requiring regular needles, clinic visits or self-injection. This burden can hinder long-term treatment. Delivering these proven medicines without injections could improve access for hundreds of thousands of Australians.

This study is exploring whether delivering two already-approved antibody medicines directly into the colon via a colonoscopy procedure, rather than by injection, allows the body to absorb them more effectively.

As a healthy volunteer, you won't be treating a condition yourself, but you'll be playing an important role in helping researchers understand this new delivery method.