phase II
enrolling now

The Knee Osteoarthritis Trial

For adults aged 40–80 with knee pain due to osteoarthritis. Conducted at Maroochy Private Hospital clinic, in Maroochydore, in the Sunshine Coast, and at our Morayfield Clinic, in Moreton Bay.
Age 40-80
day visits
Up to $1245
About this trial

A new approach to treating knee osteoarthritis

Osteoarthritis (OA) is one of Australia's most common joint conditions, affecting millions of people, particularly those over 40. It impacts the entire joint, including bone, cartilage, ligaments, and muscles, causing pain, stiffness, and reduced mobility.

If you're living with knee OA, you're not alone. Most people with OA are over 45, and many experience symptoms before age 65. Currently, very few treatments slow or stop OA progression, and most options focus only on managing pain and inflammation.
This trial is testing a single injection into the affected knee aimed at relieving pain and inflammation, and possibly slowing disease progression. Your participation could make a real difference for you and for future patients.
Eligibility

Do you qualify?

Aged 40–80 years
Medically diagnosed knee osteoarthritis with pain in one knee only
OA diagnosis in the knee more than 6 months ago
Have not responded to, or are intolerant to analgesics and/or NSAIDs
Able to attend up to 8 clinic visits and 1 phone call over 12 months
What's involved

Commitment and procedures

Visit type
day visits
total visits
8 + 1 phone call
duration
~12 months
treatment
Single injection

procedures

Physical examination
Vital signs monitoring
Medical history review
Blood test
Knee joint examination
X-ray imaging
Questionnaires
Treatment or placebo injection

treatment design

Each participant receives a single dose of investigational treatment or placebo on Day 1. Participants are randomised in a 1:1 ratio, meaning there is an equal chance of receiving either the investigational treatment or the placebo injection.
More information

Have questions? We're here to help.

Contact our recruitment team directly, they're happy to answer any questions before you apply. Please do not send personal medical information by email.
Phone
+07 5409 8640
Hours
Mon–Fri, 8am–5pm
Trial at a glance
Status
enrolling
Phase
phase II
Therapeutic Area
Ages
40-80
Duration
~12 months
Visits
8 visits, 1 phone call
Location
Maroochydore and Morayfield clinics
PROTOCOL
KOA-25-03
Reimbursement
Up to $1245

Ready to check your eligibility?

It takes less than 2 minutes to fill out our knee osteoarthritis trial form.
Apply for this trial →
We won't share your details with third parties.
This trial has been reviewed by an independent human research ethics committee.

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