A potential new way to prevent chlamydia infection
Chlamydia is one of the most common sexually transmitted infections worldwide, and one of the most misunderstood. Often called the "silent" STI, more than 80% of people who are infected experience no symptoms at all, meaning many cases go undetected and untreated. Left unchecked, chlamydia can lead to serious long-term health complications, including infertility, pelvic inflammatory disease, and increased susceptibility to other infections, such as HIV.
Currently, there is no vaccine available to prevent chlamydia. This chlamydia vaccine trial is evaluating an investigational mRNA vaccine designed to trigger an immune response that may prevent infection and reduce the spread of this common STI, offering a potential new tool in sexual health that could benefit communities worldwide.
Participants receive the investigational vaccine or placebo in three doses at 0, 2, and 6 months, followed by a follow-up period of up to 12 months after the final dose. Reimbursement of up to $3,000 is available, paid in increments after each visit and phone call.
Eligibility
Do you qualify for the chlamydia vaccine trial?
Aged 18–29 and sexually active
In good general health
No current chlamydia infection
Not pregnant, breastfeeding, or planning to become pregnant during the study
Willing to use effective contraception from 4 weeks before first dose until 4 weeks after last dose
Already have chlamydia? You may still be eligible. Once you've completed treatment and waited 30 days, you can be re-screened to see if you now qualify. Don't let a current diagnosis stop you from applying.
What's involved
Commitment and procedures
Visit type
day visits
total visits
13 + 4 phone calls
duration
18 months
treatment
3 injections
procedures at each visit
Physical examination
Vital signs monitoring
Medical history review
Blood tests
Vaginal swabs (females)
Urine sample collection (males)
Questionnaires
Rectal and oropharyngeal swab
Pregnancy test
Treatment or placebo injection
treatment design
Eligible participants will be randomly assigned to receive either the investigational chlamydia vaccine or a placebo, administered by intramuscular injection into the upper arm across three doses at 0, 2, and 6 months. Following the final dose, participants will be monitored through regular follow-up visits for up to 12 months.
More information
Have questions? We're here to help.
Contact our recruitment team directly, they're happy to answer any questions before you apply to the chlamydia vaccine trial. Please do not send personal medical information by email.
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