Cardiovascular disease (CVD), which includes heart disease, stroke, and blood vessel disorders, remains one of Australia's most significant health challenges.
1 in 6 Australians live with CVD, and it accounts for 1 in 4 deaths nationally, around 120 every day. For many people, managing blood pressure with standard medications isn't enough to adequately reduce that risk.
This trial is evaluating an investigational medication that may help reduce the risk of serious heart events, including heart attack, stroke, cardiovascular death, and heart failure, in people whose hypertension remains uncontrolled despite taking at least two blood pressure medications. Researchers will also monitor blood pressure changes, kidney health, and other important health measures throughout the trial.
treatment design
The investigational medication or placebo is administered by injection under the skin, into the abdomen, thigh, or upper arm, every six months in the clinic.
Participants will attend between 10 and 14 visits at our Sippy Downs clinic over 2.5 to 5 years, with 8 visits in the first year and then every 6 months thereafter. All procedures will be explained clearly, and participants can ask questions at any time.
