phase I
enrolling now

The Alopecia Areata Trial

For adults aged 18–75 with a diagnosis of severe alopecia areata who have lost at least half of their scalp hair for six months or more. Conducted at our South Brisbane clinic.
Age 18-75
day visits
Up to $4718
About this trial

A potential new treatment for severe alopecia areata

Alopecia areata (AA) is an autoimmune condition in which the immune system mistakenly attacks the hair follicles, causing patchy or complete hair loss on the scalp, face, and body. Over 500,000 Australians are affected by alopecia areata, and around 1 in 50 people will experience an episode at some point in their lives. Beyond the visible hair loss, people living with AA often experience nail changes, and the psychological impact can be significant, including elevated rates of stress, anxiety, and depression.

Current treatments don't work for everyone, and for those with severe forms of the condition, including total scalp, facial, and body hair loss, effective options can be limited. This trial is evaluating a new investigational treatment administered by intravenous (IV) infusion that may offer new hope for people living with severe alopecia areata.
There is a 75% chance of receiving the investigational treatment rather than a placebo, and all participants are closely monitored for one hour after each infusion by our medical team.
Eligibility

Do you qualify?

Males aged 18–60 or females aged 18–75
Have a diagnosis of severe alopecia areata: 50% loss of scalp hair or all hair on the scalp, and/or face, and body, for 6 months or more
Other types of hair loss such as traction alopecia, scarring alopecia, or male/female pattern baldness
No scalp conditions that could interfere with the trial such as psoriasis, dermatitis, or fungal infections
What's involved

Commitment and procedures

Visit type
day visits
total visits
13
duration
36 weeks
treatment
Intravenous (IV) infusion

procedures

Medical & physical examination
ECG (electrocardiogram)
Blood and urine samples
Urine pregnancy test (if applicable)
Severity of Alopecia Tool (SALT) scoring
Photography assessments (scalp, eyebrows, eyelashes)
Questionnaires
Contraception checks

treatment design

Eligible participants will be randomly assigned to receive either the investigational treatment or a placebo via IV infusion, with a 75% chance of receiving the active treatment. Each infusion lasts approximately one hour, followed by a one-hour observation period to monitor for any side effects. 

Participants will attend 13 clinic visits at our South Brisbane clinic over 36 weeks. All procedures will be explained clearly, and participants can ask questions at any time.
More information

Have questions? We're here to help.

Contact our recruitment team directly; they're happy to answer any questions before you apply. Please do not send personal medical information by email.
Phone
+07 5409 8640
Hours
Mon–Fri, 8am–5pm
Trial at a glance
Status
enrolling
Phase
phase I
Therapeutic Area
Ages
18-75
Duration
36 weeks
Visits
13 visits
Location
South Bank clinic
PROTOCOL
FB102-701
Reimbursement
Up to $4718

Ready to check your eligibility?

Takes less than 1 minute to enrol in our alopecia areata trial.
Apply for this trial →
We won't share your details with third-parties.
This trial has been reviewed by an independent human research ethics committee.

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